St. James’ college of Nursing was established in the year 2002 and situated at the beautiful river bank of Chalakudy. The College is located in the 10 acres of campus of St.James Medical Academy one and half km away from south junction of Chalakudy and two and half km away from Chalakudy railway station. It is run by St. James’ hospital Trust.The College was a long cherished desire of the diocese of Irinjalakuda and it remains as the silver Jubilee memorial of the diocese and the Episcopal ordination of its first Bishop Mar James Pazhayattil,who was heading the diocese from 1978 to 2010.The College of Nursing flourished under the expert leadership and paternal guidance of His Excellency Mar James Pazhayattil.His Excellency Mar Pauly Kannukkadan is the present patron of the college.The college is affiliated to Kerala University of Health and Allied Sciences from 2010 admission.It has the recognition and sanction by Kerala State Nursing council  and Indian Nursing council.